Author:Veliz-Cuba A and Stingler B.
Created:11/8/2016
Updated:12/19/2016
Version:1

Version Description

Description
Our model includes the two main glucose control mechanisms of catabolite repression and inducer exclusion. We show that this Boolean model is capable of predicting the ON and OFF steady states and bistability. Further, we present a reduced model which shows that lac mRNA and lactose form the core of the lac operon, and that this reduced model exhibits the same dynamics.

Tags
bistability, lac operon, E. coli

References
Veliz-Cuba A and Stigler B.Boolean models can explain bistability in the lac operon.J Comput Biol 2011 Jun18; (6) 783-94.pmid:21563979
